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Issue 67, 2012
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Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

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Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.

Graphical abstract: Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

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Publication details

The article was received on 31 May 2012, accepted on 20 Jun 2012 and first published on 21 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33913G
Citation: Chem. Commun., 2012,48, 8332-8334
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    Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

    N. Nomikou, C. Fowley, N. M. Byrne, B. McCaughan, A. P. McHale and J. F. Callan, Chem. Commun., 2012, 48, 8332
    DOI: 10.1039/C2CC33913G

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