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Palladium-catalyzed cyclization of o-alkynyltrifluoroacetanilides followed by isocyanide insertion: synthesis of 2-substituted 1H-indole-3-carboxamides

Ziwei Hu,a   Dongdong Liang,a   Jiaji Zhao,a   Jinbo Huanga and   Qiang Zhu*a  
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State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Avenue, Guangzhou 510530, China
E-mail: zhu_qiang@gibh.ac.cn;
Fax: +86-20-3201-5299 ;
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Chem. Commun., 2012,48, 7371-7373

DOI: 10.1039/C2CC33435F
Received 12 May 2012, Accepted 30 May 2012
First published online 13 Jun 2012
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