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Issue 60, 2012
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Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides

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Abstract

A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction.

Graphical abstract: Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides

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Publication details

The article was received on 09 May 2012, accepted on 06 Jun 2012 and first published on 22 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33356B
Citation: Chem. Commun., 2012,48, 7444-7446
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    Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides

    B. Shen, M. W. Bedore, A. Sniady and T. F. Jamison, Chem. Commun., 2012, 48, 7444
    DOI: 10.1039/C2CC33356B

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