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Issue 67, 2012
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Chemical speciation of nanoparticles surrounding metal-on-metal hips

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Abstract

Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr3+, with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed.

Graphical abstract: Chemical speciation of nanoparticles surrounding metal-on-metal hips

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Publication details

The article was received on 26 Apr 2012, accepted on 12 Jun 2012 and first published on 13 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33016D
Citation: Chem. Commun., 2012,48, 8335-8337
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    Chemical speciation of nanoparticles surrounding metal-on-metal hips

    A. E. Goode, J. M. Perkins, A. Sandison, C. Karunakaran, H. Cheng, D. Wall, J. A. Skinner, A. J. Hart, A. E. Porter, D. W. McComb and M. P. Ryan, Chem. Commun., 2012, 48, 8335
    DOI: 10.1039/C2CC33016D

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