One-step continuous synthesis of biocompatible gold nanorods for optical coherence tomography

Víctor Sebastián; Seung-Kon Lee; Chao Zhou; Martin F. Kraus; James G. Fujimoto; Klavs F. Jensen

doi:10.1039/C2CC32969G

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Chemical Communications

Issue 53, 2012

Urgent high quality communications from across the chemical sciences.

Impact Factor 6.169 100 Issues per Year Indexed in MEDLINE

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One-step continuous synthesis of biocompatible gold nanorods for optical coherence tomography

Víctor Sebastián,^a Seung-Kon Lee,^a Chao Zhou,^b Martin F. Kraus,^b James G. Fujimoto*^b and Klavs F. Jensen*^a

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Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, USA
E-mail: kfjensen@mit.edu

Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, USA
E-mail: jgfuji@mit.edu

Chem. Commun., 2012,48, 6654-6656

DOI: 10.1039/C2CC32969G
Received 11 Mar 2012, Accepted 10 May 2012
First published online 10 May 2012

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We present a novel one-step flow process to synthesize biocompatible gold nanorods with tunable absorption and biocompatible surface ligands. Photothermal optical coherence tomography (OCT) of human breast tissue is successfully demonstrated using tailored gold nanorods designed to have strong absorption in the near-infrared range.

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Víctor Sebastián
Seung-Kon Lee
Chao Zhou
Martin F. Kraus
James G. Fujimoto
Klavs F. Jensen

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