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Issue 54, 2012
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Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity

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Abstract

Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.

Graphical abstract: Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity

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Publication details

The article was received on 04 Apr 2012, accepted on 15 May 2012 and first published on 16 May 2012


Article type: Communication
DOI: 10.1039/C2CC32424E
Citation: Chem. Commun., 2012,48, 6833-6835
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    Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity

    D. Kim, S. Sambasivan, H. Nam, K. Hean Kim, J. Yong Kim, T. Joo, K. Lee, K. Kim and K. Han Ahn, Chem. Commun., 2012, 48, 6833
    DOI: 10.1039/C2CC32424E

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