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Issue 52, 2012
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Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

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Abstract

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

Graphical abstract: Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

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Publication details

The article was received on 23 Mar 2012, accepted on 01 May 2012 and first published on 23 May 2012


Article type: Communication
DOI: 10.1039/C2CC32147E
Citation: Chem. Commun., 2012,48, 6502-6504
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    Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

    F. Manoni, C. Cornaggia, J. Murray, S. Tallon and S. J. Connon, Chem. Commun., 2012, 48, 6502
    DOI: 10.1039/C2CC32147E

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