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Issue 31, 2012
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Synthesis of polysaccharide-b-PEG block copolymers by oxime click

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Abstract

The oxime click reaction is shown to be a straightforward methodology for the synthesis of poly(ethylene glycol) (PEG)-polysaccharide diblock copolymers. The method is applicable to unmodified polysaccharides with a reductive end as demonstrated for dextran, hyaluronic acid and chitosan. Notably the oxime click reaction is applied for the first time to the end modification of polysaccharides.

Graphical abstract: Synthesis of polysaccharide-b-PEG block copolymers by oxime click

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Publication details

The article was received on 01 Feb 2012, accepted on 23 Feb 2012 and first published on 24 Feb 2012


Article type: Communication
DOI: 10.1039/C2CC30726J
Citation: Chem. Commun., 2012,48, 3781-3783
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    Synthesis of polysaccharide-b-PEG block copolymers by oxime click

    R. Novoa-Carballal and A. H. E. Müller, Chem. Commun., 2012, 48, 3781
    DOI: 10.1039/C2CC30726J

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