Issue 39, 2012

Fluorescence turn-on detection of hypochlorous acidvia HOCl-promoted dihydrofluorescein-etheroxidation and its application in vivo

Abstract

We report three new water-soluble dihydrofluorescein-ether probes FCN1, FCN2 and FCN3 for the detection of hypochlorous acid (HOCl), which were designed on the basis of a specific HOCl-promoted oxidation reaction. This work also provided a useful method to monitor the accumulated HOCl in specific organelles using a zebrafish model.

Graphical abstract: Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

Supplementary files

Article information

Article type
Communication
Submitted
12 Jan 2012
Accepted
15 Feb 2012
First published
17 Feb 2012

Chem. Commun., 2012,48, 4677-4679

Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

Y. Zhou, J. Li, K. Chu, K. Liu, C. Yao and J. Li, Chem. Commun., 2012, 48, 4677 DOI: 10.1039/C2CC30265A

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