Issue 47, 2012

Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides

Abstract

Disulfide- and terminal alkyne-modified magnetic silica particles (DA-MSPs) were synthesized and used to covalently capture and reductively release azido glycopeptides via click chemistry and dithiothreitol treatment. Using DA-MSPs, an efficient and specific enrichment method for separating azido glycopeptides has been developed.

Graphical abstract: Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides

Supplementary files

Article information

Article type
Communication
Submitted
30 Dec 2011
Accepted
17 Apr 2012
First published
18 Apr 2012

Chem. Commun., 2012,48, 5907-5909

Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides

S. Wang, W. Xie, X. Zhang, X. Zou and Y. Zhang, Chem. Commun., 2012, 48, 5907 DOI: 10.1039/C2CC18160F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements