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Issue 21, 2012
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An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

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Abstract

An aptamer microarray was directly fabricated on a MALDI target plate for high-throughput insulin detection. High sensitivities were observed both in standard solutions (5 ng mL−1, 0.86 nM) and serum sample (20 ng mL−1, 3.4 nM). This method shows great promise in the field of biomarker detection.

Graphical abstract: An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

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Publication details

The article was received on 21 Dec 2011, accepted on 19 Jan 2012 and first published on 20 Jan 2012


Article type: Communication
DOI: 10.1039/C2CC17997K
Citation: Chem. Commun., 2012,48, 2689-2691
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    An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

    X. Zhang, S. Zhu, C. Deng and X. Zhang, Chem. Commun., 2012, 48, 2689
    DOI: 10.1039/C2CC17997K

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