Issue 15, 2012
From the journal:

Chemical Communications

Ternary resin-bound dynamic combinatorial chemistry†

Anna V. Gromova,a   Joseph M. Ciszewskia  and  Benjamin L. Miller*a  

* Corresponding authors

a Department of Dermatology, University of Rochester Medical Center, Rochester, New York, USA
E-mail: Benjamin_Miller@urmc.rochester.edu
Fax: 585-273-1346
Tel: 585-275-9805

Abstract

The ability to carry out simultaneous orthogonal exchange chemistries has opened new opportunities for increasing the numerical and structural diversity accessible to Dynamic Combinatorial Chemistry. We present proof-of-concept experiments demonstrating this concept is transferrable to resin-bound DCC, facilitating the generation and analysis of libraries with greater structural diversity.

Graphical abstract: Ternary resin-bound dynamic combinatorial chemistry

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Article information

DOI
https://doi.org/10.1039/C2CC17192A
Article type
Communication
Submitted
18 Nov 2011
Accepted
19 Dec 2011
First published
20 Dec 2011

Chem. Commun., 2012,48, 2131-2133

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Ternary resin-bound dynamic combinatorial chemistry

A. V. Gromova, J. M. Ciszewski and B. L. Miller, Chem. Commun., 2012, 48, 2131 DOI: 10.1039/C2CC17192A

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