The melting temperature of duplex DNA is much higher in polyanions than in non-ionic polymers with similar ionic strength, suggesting an additional electrostatic contribution on top of the excluded volume effect.
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DNA duplex stabilization in crowded polyanion solutions
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Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Canada
E-mail: liujw@uwaterloo.ca ;
Fax: +1 519 7460435 ;
Tel: +1 519 8884567 Ext. 38919
E-mail: liujw@uwaterloo.ca ;
Fax: +1 519 7460435 ;
Tel: +1 519 8884567 Ext. 38919
Chem. Commun., 2013,49, 1306-1308
DOI: 10.1039/C2CC38627E
Received 02 Nov 2012, Accepted 21 Dec 2012
First published online 21 Dec 2012
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