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Department of Chemistry and Institute of Bio-Physico Sensor Technology, Pusan National University, Busan 609-735, South Korea
E-mail: ybshim@pusan.ac.kr
; Fax: +82 51-514-2430
; Tel: +82 51-510-2244
Chem. Commun., 2013,49, 1900-1902
DOI:
10.1039/C2CC38235K
Received
15 Nov 2012,
Accepted
20 Dec 2012
First published online
21 Dec 2012
Simple and general cancer cell detection methods are required in point-of-care diagnostics. Herein, the interaction between an anticancer drug, daunomycin, and cancer cell membrane components has been studied using an aptamer probe immobilized on a conducting polymer–gold nanoparticle composite film through electrochemical and fluorescence methods and applied to the quantitative detection of cancer cells. The developed method differentiates between cancerous and noncancerous cells effectively.
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