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Issue 24, 2013
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Layer by layer assembly of biotinylated protein networks for signal amplification

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Abstract

Described herein is a unique and inexpensive method that outperforms commercial methods that amplify the streptavidin–biotin recognition event. Amplification induced by streptavidin and biotinylated protein causes the formation of a large detectable polymer. This approach enjoys a 100-fold decrease in detection limit in comparison with the commercial methods.

Graphical abstract: Layer by layer assembly of biotinylated protein networks for signal amplification

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Publication details

The article was received on 15 Nov 2012, accepted on 07 Jan 2013 and first published on 07 Jan 2013


Article type: Communication
DOI: 10.1039/C2CC38233D
Citation: Chem. Commun., 2013,49, 2397-2399
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    Layer by layer assembly of biotinylated protein networks for signal amplification

    Y. W. Chu, B. Y. Wang, H. Lin, T. Lin, Y. Hung, D. A. Engebretson, W. Lee and J. R. Carey, Chem. Commun., 2013, 49, 2397
    DOI: 10.1039/C2CC38233D

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