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Departments of Chemistry and Molecular and Computational Biology, University of Southern California, Los Angeles, USA
E-mail: matthew.pratt@usc.edu
; Fax: +1 213 740 0930
; Tel: +1 213 740 3014
Chem. Commun., 2013,49, 4328-4330
DOI:
10.1039/C2CC37963E
Received
02 Nov 2012,
Accepted
03 Dec 2012
First published online
03 Dec 2012
Metabolic chemical reporters of glycosylation allow for the visualization and identification of a variety of glycoconjugates by taking advantage of the promiscuity of carbohydrate metabolism. Here we describe the synthesis and characterization of metabolic chemical reporters bearing an N-propargyloxycarbamate (Poc) group that creates discrimination between glycosylation pathways.
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