A prodrug nanoassembly entrapping drugs as a tumor-targeted delivery system

Zhefan Yuan; Xiaoqing Yi; Jing Zhang; Sixue Cheng; Renxi Zhuo; Feng Li

doi:10.1039/C2CC37798E

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Chemical Communications

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A prodrug nanoassembly entrapping drugs as a tumor-targeted delivery system

Zhefan Yuan,^a Xiaoqing Yi,^a Jing Zhang,^a Sixue Cheng,^a Renxi Zhuo^a and Feng Li*^a

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Key Laboratory of Biomedical Polymers of Ministry of Education, College of Chemistry and Molecular Science, Wuhan University, Wuhan, P. R. China
E-mail: lfsj2004@hotmail.com

Chem. Commun., 2013,49, 801-803

DOI: 10.1039/C2CC37798E
Received 01 Aug 2012, Accepted 03 Dec 2012
First published online 03 Dec 2012

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We presented here a targeted drug delivery system, biotinylated polyethylene glycol prodrug loading with free drugs (doxorubicin or camptothecin), which showed high drug loading capacity and superior targeted therapeutic efficacy for cancerous cells.

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Zhefan Yuan
Xiaoqing Yi
Jing Zhang
Sixue Cheng
Renxi Zhuo
Feng Li

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