An efficient organocatalyzed strategy for the synthesis of 3-amino-1-indanols has been developed. This method is complementary to the conventional Friedel–Crafts strategy. It is also applicable to the synthesis of enantioenriched 3-amino-1-indanols.
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Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction
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Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China
E-mail: sunjw@ust.hk ;
Fax: +852 23581594 ;
Tel: +852 23587351
E-mail: sunjw@ust.hk ;
Fax: +852 23581594 ;
Tel: +852 23587351
Chem. Commun., 2013,49, 4361-4363
DOI: 10.1039/C2CC37102B
Received 29 Sep 2012, Accepted 02 Nov 2012
First published online 05 Nov 2012
This article is part of themed collection:
Emerging Investigators 2013
Chemical Communications
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