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Issue 39, 2013
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Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

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Abstract

An efficient organocatalyzed strategy for the synthesis of 3-amino-1-indanols has been developed. This method is complementary to the conventional Friedel–Crafts strategy. It is also applicable to the synthesis of enantioenriched 3-amino-1-indanols.

Graphical abstract: Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

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Publication details

The article was received on 29 Sep 2012, accepted on 02 Nov 2012 and first published on 05 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC37102B
Citation: Chem. Commun., 2013,49, 4361-4363
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    Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

    H. Qian, W. Zhao, H. H-Y. Sung, I. D. Williams and J. Sun, Chem. Commun., 2013, 49, 4361
    DOI: 10.1039/C2CC37102B

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