A facile, universal and label-free fluorescence turn-on amplification strategy for the detection of DNA has been reported, which can achieve ultralow femtomolar detection of a target gene sequence with high selectivity.
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Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching
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a
State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: jren@ciac.jl.cn
E-mail: jren@ciac.jl.cn
b
Graduate School of the Chinese Academy of Sciences, Beijing, China
Chem. Commun., 2012,48, 11662-11664
DOI: 10.1039/C2CC37039E
Received 28 Sep 2012, Accepted 18 Oct 2012
First published online 18 Oct 2012
Chemical Communications
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