This Communication describes a thermally-stable small molecule and a corresponding assay strategy that autonomously amplifies a colorimetric signal when a specific enzyme biomarker is detected.
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A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents
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The Pennsylvania State University, 104 Chemistry Bldg., University Park, USA
E-mail: sphillips@psu.edu ;
Fax: +1 814 865 5235 ;
Tel: +1 814 867 2502
E-mail: sphillips@psu.edu ;
Fax: +1 814 865 5235 ;
Tel: +1 814 867 2502
Chem. Commun., 2013,49, 394-396
DOI: 10.1039/C2CC36861G
Received 20 Sep 2012, Accepted 01 Nov 2012
First published online 05 Nov 2012
Chemical Communications
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