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Issue 4, 2013
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A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

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Abstract

A diselenide containing fluorescent probe based on a fluorescein scaffold for thiols was developed. The fluorescent probe exhibited rapid response, high selectivity and reversibility. Confocal fluorescence microscopy was used to visualize the redox changes mediated by thiols and reactive oxygen species in living HeLa cells.

Graphical abstract: A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

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Publication details

The article was received on 20 Sep 2012, accepted on 30 Oct 2012 and first published on 31 Oct 2012


Article type: Communication
DOI: 10.1039/C2CC36839K
Citation: Chem. Commun., 2013,49, 391-393
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    A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

    Z. Lou, P. Li, X. Sun, S. Yang, B. Wang and K. Han, Chem. Commun., 2013, 49, 391
    DOI: 10.1039/C2CC36839K

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