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Issue 97, 2012
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One-step synthesis of novel glycosyltransferase inhibitors

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Abstract

A one-step synthesis of two 5-CF3 UDP-sugars is reported. These non-natural sugar-nucleotides are micromolar inhibitors of two different galactosyltransferases.

Graphical abstract: One-step synthesis of novel glycosyltransferase inhibitors

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Publication details

The article was received on 18 Sep 2012, accepted on 23 Oct 2012 and first published on 05 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC36798J
Citation: Chem. Commun., 2012,48, 11856-11858
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    One-step synthesis of novel glycosyltransferase inhibitors

    A. Evitt, L. M. Tedaldi and G. K. Wagner, Chem. Commun., 2012, 48, 11856
    DOI: 10.1039/C2CC36798J

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