The novel palladium-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid with aryl and heteroaryl bromides including benzenes, naphthalenes, pyridines and quinolines for C–C bond formation have been successfully achieved.
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Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid
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a
The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, PR China
E-mail: wyj@zzu.edu.cn ;
Tel: +86 371 6776 7993
E-mail: wyj@zzu.edu.cn ;
Tel: +86 371 6776 7993
b
Tetranov Biopharm, LLC, 75 Daxue Road, Zhengzhou, PR China
c
Tetranov International, Inc. 100 Jersey Avenue, Suite A340, New Brunswick, USA
E-mail: yusheng.wu@tetranovglobal.com ;
Fax: +1 732 253 7327 ;
Tel: +1 732 253 7326
E-mail: yusheng.wu@tetranovglobal.com ;
Fax: +1 732 253 7327 ;
Tel: +1 732 253 7326
Chem. Commun., 2013,49, 312-314
DOI: 10.1039/C2CC36720C
Received 15 Sep 2012, Accepted 09 Nov 2012
First published online 09 Nov 2012
Chemical Communications
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