An efficient one-step synthesis of multi-functionalized oxazole derivatives is achieved in high yield by dirhodium(II)-catalyzed reactions of styryl diazoacetate with aryl oximes.
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Efficient synthesis of oxazoles by dirhodium(II)-catalyzed reactions of styryl diazoacetate with oximes
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a
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, USA
E-mail: mdoyle3@umd.edu
E-mail: mdoyle3@umd.edu
b
Shanghai Engineering Research Center for Molecular Therapeutics and Institute of Drug Discovery and Development, East China Normal University, 3663 Zhongshan Bei Road, Shanghai 200062, China
Chem. Commun., 2012,48, 11522-11524
DOI: 10.1039/C2CC36537E
Received 07 Sep 2012, Accepted 11 Oct 2012
First published online 12 Oct 2012
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