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Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase

Meiling Lu,a   Yan Huang,a   Mark A. White,b   Xuri Wu,a   Nan Liu,a   Xiaodong Cheng*bc and   Yijun Chen*a  
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Laboratory of Chemical Biology and State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjia Street, Nanjing, People's Republic of China
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Sealy Center for Structural Biology and Molecular Biophysics, The University of Texas Medical Branch, Galveston, USA
Department of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, USA
Chem. Commun., 2012,48, 11352-11354

DOI: 10.1039/C2CC36334H
Received 31 Aug 2012, Accepted 08 Oct 2012
First published online 08 Oct 2012
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