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Issue 1, 2013
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A CO2-switchable polymer brush for reversible capture and release of proteins

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Abstract

We report on a polymer brush that can be switched between extended (hydrated) and collapsed (dehydrated) chain conformational states just by passing CO2 and an inert gas like N2 in solution alternately. This conformational change allows for reversible adsorption and release of a protein. In contrast to adding acids and bases for pH change, using gases as the trigger makes it possible to repeat the switching cycle many times without salt accumulation.

Graphical abstract: A CO2-switchable polymer brush for reversible capture and release of proteins

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Publication details

The article was received on 29 Aug 2012, accepted on 08 Nov 2012 and first published on 09 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC36284H
Citation: Chem. Commun., 2013,49, 90-92
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    A CO2-switchable polymer brush for reversible capture and release of proteins

    S. Kumar, X. Tong, Y. L. Dory, M. Lepage and Y. Zhao, Chem. Commun., 2013, 49, 90
    DOI: 10.1039/C2CC36284H

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