A tandem reaction initiated by Au(I)-catalyzed C1–C5 cyclization of enediynes bearing an internal carboxy nucleophile has been developed, providing a distinctive methodology for the assembly of fused indenes including indeno[1,2-c]isochromen-5(11H)-ones and indeno[1,2-b]pyran-2(5H)-ones. A mechanism involving the concerted formation of the five- and six-membered rings was proposed.
Chemical Communications
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