Novel copolymers containing both anionic and cationic pH-sensitive moieties were reported. These amphoteric copolymers exhibited special closed-loop reversible sol–gel–sol phase transitions in response to both pH and temperature.
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Dually cationic and anionic pH/temperature-sensitive injectable hydrogels and potential application as a protein carrier
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Theranostic Macromolecules Research Center, Department of Polymer Science and Engineering, Sungkyunkwan University, Suwon, South Korea
E-mail: dslee@skku.edu ;
Fax: +82 31 299 6857 ;
Tel: +82 31 290 7282
E-mail: dslee@skku.edu ;
Fax: +82 31 299 6857 ;
Tel: +82 31 290 7282
Chem. Commun., 2012,48, 10951-10953
DOI: 10.1039/C2CC36134E
Received 23 Aug 2012, Accepted 23 Sep 2012
First published online 25 Sep 2012
Chemical Communications
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