Jump to main content
Jump to site search

Issue 89, 2012
Previous Article Next Article

Effects of fullerene derivatives on bioluminescence and application for protease detection

Author affiliations

Abstract

The effects of two C60 derivatives: C60[C(COOH)2]3 and C60(NH2)x(OH)y, have been investigated on the bioluminescence of humanized Gaussia luciferase (hGluc) for the first time. Utilizing the dual properties of carboxyl C60 with luminescence quenching and free radicals scavenging, a novel BRET system was constructed for protease detection with high sensitivity.

Graphical abstract: Effects of fullerene derivatives on bioluminescence and application for protease detection

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 22 Jul 2012, accepted on 19 Sep 2012 and first published on 21 Sep 2012


Article type: Communication
DOI: 10.1039/C2CC36099C
Citation: Chem. Commun., 2012,48, 11011-11013
  •   Request permissions

    Effects of fullerene derivatives on bioluminescence and application for protease detection

    J. Yu, M. Guan, F. Li, Z. Zhang, C. Wang, C. Shu, H. Wei and X. Zhang, Chem. Commun., 2012, 48, 11011
    DOI: 10.1039/C2CC36099C

Search articles by author