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Issue 93, 2012
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Delivery, stabilization, and spatiotemporal activation of cargo molecules in cells with positively charged nanoparticles

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Abstract

Positively charged photodegradable nanoparticles that simultaneously encapsulated various compounds including small and large molecules were prepared. The nanoparticles were internalized to the cell by endocytosis and were stable within the cells for at least 4 days. The encapsulated molecules were released into the cytosol using light stimuli.

Graphical abstract: Delivery, stabilization, and spatiotemporal activation of cargo molecules in cells with positively charged nanoparticles

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Publication details

The article was received on 01 Aug 2012, accepted on 08 Oct 2012 and first published on 09 Oct 2012


Article type: Communication
DOI: 10.1039/C2CC35567A
Citation: Chem. Commun., 2012,48, 11461-11463
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    Delivery, stabilization, and spatiotemporal activation of cargo molecules in cells with positively charged nanoparticles

    S. Murayama, T. Nishiyama, K. Takagi, F. Ishizuka, T. Santa and M. Kato, Chem. Commun., 2012, 48, 11461
    DOI: 10.1039/C2CC35567A

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