We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.
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Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection
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Jiangsu Key Laboratory of New Power Batteries, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, P.R. China
E-mail: wuping@njnu.edu.cn ;
Fax: +86 25 85891767 ;
Tel: +86 25 85891780
E-mail: wuping@njnu.edu.cn ;
Fax: +86 25 85891767 ;
Tel: +86 25 85891780
Chem. Commun., 2012,48, 10718-10720
DOI: 10.1039/C2CC35564G
Received 01 Aug 2012, Accepted 20 Aug 2012
First published online 21 Aug 2012
Chemical Communications
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