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Issue 78, 2012
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Chemoenzymatic preparation of germacrene analogues

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Abstract

A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.

Graphical abstract: Chemoenzymatic preparation of germacrene analogues

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Publication details

The article was received on 31 Jul 2012, accepted on 14 Aug 2012 and first published on 15 Aug 2012


Article type: Communication
DOI: 10.1039/C2CC35542F
Citation: Chem. Commun., 2012,48, 9702-9704
  • Open access: Creative Commons BY license
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    Chemoenzymatic preparation of germacrene analogues

    O. Cascón, S. Touchet, D. J. Miller, V. Gonzalez, J. A. Faraldos and R. K. Allemann, Chem. Commun., 2012, 48, 9702
    DOI: 10.1039/C2CC35542F

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