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Issue 86, 2012
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Copper-catalyzed intramolecular direct amination of sp2 C–H bonds for the synthesis of N-aryl acridones

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Abstract

A copper-catalyzed approach for the synthesis of N-aryl acridones via sp2 C–H bond amination using air as oxidant under neutral conditions is disclosed. This reaction not only provides a complementary method for synthesizing medicinally important acridones, but also offers a new strategy for sp2 C–H bond amination.

Graphical abstract: Copper-catalyzed intramolecular direct amination of sp2 C–H bonds for the synthesis of N-aryl acridones

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Publication details

The article was received on 27 Jul 2012, accepted on 01 Sep 2012 and first published on 03 Sep 2012


Article type: Communication
DOI: 10.1039/C2CC35425J
Citation: Chem. Commun., 2012,48, 10678-10680
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    Copper-catalyzed intramolecular direct amination of sp2 C–H bonds for the synthesis of N-aryl acridones

    W. Zhou, Y. Liu, Y. Yang and G. Deng, Chem. Commun., 2012, 48, 10678
    DOI: 10.1039/C2CC35425J

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