Issue 86, 2012
From the journal:

Chemical Communications

Directed patterning of the self-assembled silk-elastin-like nanofibers using a nanomechanical stimulus†

Sara Johnson,a   Young Koan Ko,b   Nitinun Varongchayakul,b   Sunhee Lee,f   Joseph Cappello,d   Hamidreza Ghandehari,de   Sang Bok Lee,cf   Santiago D. Solares*g  and  Joonil Seog*b  

* Corresponding authors

a Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA

b Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA
E-mail: jseog@umd.edu
Fax: +1 301-314-2029
Tel: +1 301-405-1885

c Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA

d Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, UT, USA

e Department of Bioengineering and Utah Center for Nanomedicine, University of Utah, UT, USA

f Graduate School of Nanoscience and Technology (WCU), Korea Advanced Institute of Science and Technology, Daejeon, Korea

g Department of Mechanical Engineering, University of Maryland, College Park, MD, USA

Abstract

We investigate the effects of the frequency and density of a nanomechanical stimulus on nucleation and growth of silk-elastin-like protein polymer (SELP) nanofibers. Repetitive tappings are crucial to create nucleation areas and a potential molecular level mechanism was proposed. Using this technique mechanically guided nanofiber patterns were successfully created.

Graphical abstract: Directed patterning of the self-assembled silk-elastin-like nanofibers using a nanomechanical stimulus

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Article information

DOI
https://doi.org/10.1039/C2CC35384A
Article type
Communication
Submitted
25 Jul 2012
Accepted
11 Sep 2012
First published
11 Sep 2012

Chem. Commun., 2012,48, 10654-10656

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Directed patterning of the self-assembled silk-elastin-like nanofibers using a nanomechanical stimulus

S. Johnson, Y. K. Ko, N. Varongchayakul, S. Lee, J. Cappello, H. Ghandehari, S. B. Lee, S. D. Solares and J. Seog, Chem. Commun., 2012, 48, 10654 DOI: 10.1039/C2CC35384A

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