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Issue 79, 2012
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A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

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Abstract

1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of α-amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH2Cl2. This methodology was utilized to synthesize 2-benzoyl quinolines.

Graphical abstract: A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

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Publication details

The article was received on 20 Jul 2012, accepted on 18 Aug 2012 and first published on 20 Aug 2012


Article type: Communication
DOI: 10.1039/C2CC35235D
Citation: Chem. Commun., 2012,48, 9927-9929
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    A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

    Z. Mao, H. Qu, Y. Zhao and X. Lin, Chem. Commun., 2012, 48, 9927
    DOI: 10.1039/C2CC35235D

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