1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of α-amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH2Cl2. This methodology was utilized to synthesize 2-benzoyl quinolines.
Urgent high quality communications from across the chemical sciences.
Impact Factor
6.169
100 Issues per Year
Indexed in MEDLINE
Communication
A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines
Show Affiliations
Hide Affiliations
*
Corresponding authors
a
Department of Chemistry, Zhejiang University, Hangzhou 310027, China
E-mail: lxfok@zju.edu.cn
E-mail: lxfok@zju.edu.cn
Chem. Commun., 2012,48, 9927-9929
DOI: 10.1039/C2CC35235D
Received 20 Jul 2012, Accepted 18 Aug 2012
First published online 20 Aug 2012
Chemical Communications
- Information Point
Supplementary Info
-
Supplementary information
PDF (2378K) -
Crystal structure data
TXT (16K)