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Issue 86, 2012
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Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles

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Abstract

A novel strategy of dual signal amplification was developed using circular strand-replacement DNA polymerization with a molecular beacon as a switch and silver enhancement on magnetic nanoparticles for the specific Raman spectroscopic detection of DNA down to the sub-picomolar level.

Graphical abstract: Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles

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Publication details

The article was received on 19 Jul 2012, accepted on 12 Aug 2012 and first published on 13 Aug 2012


Article type: Communication
DOI: 10.1039/C2CC35203F
Citation: Chem. Commun., 2012,48, 10603-10605
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    Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles

    F. Gao, Z. Zhu, J. Lei and H. Ju, Chem. Commun., 2012, 48, 10603
    DOI: 10.1039/C2CC35203F

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