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State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, PO Box 98, No. 15 BEISANHUAN East Road, Beijing 100029, P. R. China
; Fax: +86-10-64425385
Chem. Commun., 2012,48, 10349-10351
17 Jul 2012,
30 Aug 2012
First published online
31 Aug 2012
Highly efficient and enantioselective asymmetric Henry–Michael one-pot reaction has been achieved on bifunctional heterogeneous catalysts with inherent achiral hydroxyls as acidic sites and immobilized chiral amines as basic sites. Final products were afforded in yields of up to 85% and ee of 99%.
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