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Issue 79, 2012
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Selective syntheses of no-carrier-added 2- and 3-[18F]fluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates

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Abstract

No-carrier-added 2- and 3-[18F]fluorohalopyridines were readily synthesized as potentially useful labeling synthons for prospective PET radiotracers through the selective radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates, themselves conveniently prepared in a single pot from iodohalopyridines.

Graphical abstract: Selective syntheses of no-carrier-added 2- and 3-[18F]fluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates

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Publication details

The article was received on 12 Jul 2012, accepted on 17 Aug 2012 and first published on 20 Aug 2012


Article type: Communication
DOI: 10.1039/C2CC35005J
Citation: Chem. Commun., 2012,48, 9921-9923
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    Selective syntheses of no-carrier-added 2- and 3-[18F]fluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates

    J. Chun and V. W. Pike, Chem. Commun., 2012, 48, 9921
    DOI: 10.1039/C2CC35005J

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