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School of Biotechnology, Department of Biochemistry, Royal Institute of Technology (KTH), AlbaNova, SE-106 91 Stockholm, Sweden
; Fax: +46 8 5537 8468
; Tel: +46 8 5537 8364
The enzyme Candida antarctica lipase B was subjected to site directed mutagenesis suggested by molecular modelling. The selectivity for the enzyme increased towards a range of diols over their corresponding monoesters as an effect of the mutations.
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