Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to ‘turn-on’ the activity of apo-GOx and thus generates a measurable response.
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GOx signaling triggered by aptamer-based ATP detection
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Department of Chemistry, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, USA
E-mail: mali2@xula.edu ;
Fax: +1 504 520 7942 ;
Tel: +1 504 520 7378
E-mail: mali2@xula.edu ;
Fax: +1 504 520 7942 ;
Tel: +1 504 520 7378
Chem. Commun., 2012,48, 9284-9286
DOI: 10.1039/C2CC34279K
Received 14 Jun 2012, Accepted 27 Jul 2012
First published online 27 Jul 2012
Chemical Communications
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