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Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, Guohe Road 325, Shanghai 200433, P.R. China
; Fax: +86-21-81871225
State Key Laboratory of New drug and Pharmaceutical Process; Center for Pharmacological Evaluation and Research, Shanghai Institute of Pharmaceutical Industry, Zhongshanbeiyi Road 1111, Shanghai 200437, P.R. China
; Fax: +86-21-6544936
Chem. Commun., 2012,48, 8781-8783
10 Jun 2012,
12 Jul 2012
First published online
12 Jul 2012
Spirolactonized Si-rhodamine was prepared as a platform to construct Si-rhodamine-based probes by following the design strategy widely used in rhodamine systems. Among them, the reaction-based probe SiR-Hg was operated for NIR sensing and bioimaging of Hg2+ in living cells based on the similar irreversible spirolactam ring-opening process to traditional rhodamine derivatives.
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