Jump to main content
Jump to site search

Issue 70, 2012
Previous Article Next Article

gem-Dialkylthio vinylallenes: alkylthio-regulated reactivity and application in the divergent synthesis of pyrroles and thiophenes

Author affiliations

Abstract

gem-Dialkylthio vinylallenes were obtained for the first time and applied to the divergent synthesis of fully-substituted pyrroles and thiophenes by domino cyclizations. These two cyclization pathways were regulated by alkylthio groups. Plausible reaction mechanisms were presented and supported by DFT calculations. An unprecedented metal-free carbothiolation was discovered in the formation of thiophenes.

Graphical abstract: gem-Dialkylthio vinylallenes: alkylthio-regulated reactivity and application in the divergent synthesis of pyrroles and thiophenes

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 May 2012, accepted on 12 Jul 2012 and first published on 26 Jul 2012


Article type: Communication
DOI: 10.1039/C2CC33857B
Citation: Chem. Commun., 2012,48, 8802-8804
  •   Request permissions

    gem-Dialkylthio vinylallenes: alkylthio-regulated reactivity and application in the divergent synthesis of pyrroles and thiophenes

    Z. Fang, H. Yuan, Y. Liu, Z. Tong, H. Li, J. Yang, B. Barry, J. Liu, P. Liao, J. Zhang, Q. Liu and X. Bi, Chem. Commun., 2012, 48, 8802
    DOI: 10.1039/C2CC33857B

Search articles by author

Spotlight

Advertisements