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Issue 73, 2012
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Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

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Abstract

We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector.

Graphical abstract: Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

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Publication details

The article was received on 25 May 2012, accepted on 23 Jul 2012 and first published on 24 Jul 2012


Article type: Communication
DOI: 10.1039/C2CC33774F
Citation: Chem. Commun., 2012,48, 9144-9146
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    Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

    J. Kim, S. Cho, D. Kang, J. B. Edel, S. Chang, A. J. deMello and D. O'Hare, Chem. Commun., 2012, 48, 9144
    DOI: 10.1039/C2CC33774F

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