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Issue 70, 2012
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Membrane protein distribution in composite polymerlipid thin films

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Abstract

We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid drives the protein to a fluid phase, mechanically more similar to a cellular bilayer.

Graphical abstract: Membrane protein distribution in composite polymer–lipid thin films

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Publication details

The article was received on 21 Apr 2012, accepted on 13 Jul 2012 and first published on 26 Jul 2012


Article type: Communication
DOI: 10.1039/C2CC32851H
Citation: Chem. Commun., 2012,48, 8811-8813
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    Membrane protein distribution in composite polymerlipid thin films

    J. Thoma, S. Belegrinou, P. Rossbach, M. Grzelakowski, K. Kita-Tokarczyk and W. Meier, Chem. Commun., 2012, 48, 8811
    DOI: 10.1039/C2CC32851H

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