Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 51, 2012
Previous Article Next Article

Microwave accelerated Glaser–Hay macrocyclizations at high concentrations

Author affiliations

Abstract

Efficient macrocyclization can be conducted at high concentrations employing microwave irradiation and a phase separation strategy. The rate of the Glaser–Hay macrocyclization is accelerated using microwave irradiation and reaction times decreased from 48 h to 1–6 h, depending on the nature of the substrate. Macrocyclization concentrations could be increased up to 0.1 M compared to traditional concentrations (0.2 mM).

Graphical abstract: Microwave accelerated Glaser–Hay macrocyclizations at high concentrations

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 05 Apr 2012, accepted on 03 May 2012 and first published on 04 May 2012


Article type: Communication
DOI: 10.1039/C2CC32464D
Citation: Chem. Commun., 2012,48, 6420-6422
  •   Request permissions

    Microwave accelerated Glaser–Hay macrocyclizations at high concentrations

    A. Bédard and S. K. Collins, Chem. Commun., 2012, 48, 6420
    DOI: 10.1039/C2CC32464D

Search articles by author