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Issue 44, 2012
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A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots

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Abstract

Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.

Graphical abstract: A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots

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Publication details

The article was received on 16 Mar 2012, accepted on 05 Apr 2012 and first published on 05 Apr 2012


Article type: Communication
DOI: 10.1039/C2CC31951A
Citation: Chem. Commun., 2012,48, 5428-5430
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    A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots

    O. Kovtun, E. J. Ross, I. D. Tomlinson and S. J. Rosenthal, Chem. Commun., 2012, 48, 5428
    DOI: 10.1039/C2CC31951A

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