The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.
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The role of lipophilicity in transmembrane anion transport
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Corresponding authors
a
Centre for Systems Chemistry, Stratingh Institute, University of Groningen, 9747 AG Groningen, The Netherlands
b
Departamento de Química, CICECO and Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal
c
Departamento de Química, Facultad de Ciencias, Universidad de Burgos, 09001 Burgos, Spain
E-mail: rquesada@ubu.es
E-mail: rquesada@ubu.es
Chem. Commun., 2012,48, 5274-5276
DOI: 10.1039/C2CC31825C
Received 12 Mar 2012, Accepted 10 Apr 2012
First published online 24 Apr 2012
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