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Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones

Liang-Liang Wang,ab   Jian-Fei Bai,ab   Lin Peng,a   Liang-Wen Qi,ab   Li-Na Jia,ab   Yun-Long Guo,ab   Xi-Ya Luo,ab   Xiao-Ying Xu*a and   Li-Xin Wang*a  
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Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China
E-mail: wlxioc@cioc.ac.cn, xuxy@cioc.ac.cn
Graduate School of Chinese Academy of Sciences, Beijing, China
Chem. Commun., 2012,48, 5175-5177

DOI: 10.1039/C2CC30746D
Received 02 Feb 2012, Accepted 30 Mar 2012
First published online 02 Apr 2012
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