Jump to main content
Jump to site search

Issue 37, 2012
Previous Article Next Article

Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

Author affiliations

Abstract

Phosphine-boronates R2P(o-C6H4)B(OR′)2 have been evaluated as bifunctional organocatalysts for the Michael addition of malonate pronucleophiles to methylvinylketone. The presence of the Lewis acidic boron center adjacent to phosphorus significantly improves catalytic performance. Isolation and complete characterization of a key intermediate, namely a β-phosphonium enolate, substantiate the role of the Lewis acidic moiety in the catalytic process.

Graphical abstract: Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 17 Jan 2012, accepted on 14 Mar 2012 and first published on 15 Mar 2012


Article type: Communication
DOI: 10.1039/C2CC30399J
Citation: Chem. Commun., 2012,48, 4495-4497
  •   Request permissions

    Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

    O. Baslé, S. Porcel, S. Ladeira, G. Bouhadir and D. Bourissou, Chem. Commun., 2012, 48, 4495
    DOI: 10.1039/C2CC30399J

Search articles by author