Jump to main content
Jump to site search

Issue 42, 2012
Previous Article Next Article

Shape persistence delivers lock-and-key chloride binding in triazolophanes

Author affiliations

Abstract

Triazolophanes have recently surfaced as a new class of shape-persistent macrocycles that bind anions. Bearing only triazole- and phenyl-derived CH hydrogen bond donors, these receptors have shown extraordinary Cl binding strengths (>106 M−1, CH2Cl2). The attributes of the triazolophane that are responsible are presented herein alongside recent literature accounts that have utilized similar strategies in new and exciting supramolecular systems. This review describes how triazolophanes leverage the structural pre-organization characteristic of spherands to take advantage of non-traditional hydrogen bonds originating from extrinsic CH donors.

Graphical abstract: Shape persistence delivers lock-and-key chloride binding in triazolophanes

Back to tab navigation

Publication details

The article was received on 29 Nov 2011, accepted on 21 Dec 2011 and first published on 17 Jan 2012


Article type: Feature Article
DOI: 10.1039/C2CC17459F
Citation: Chem. Commun., 2012,48, 5065-5075
  •   Request permissions

    Shape persistence delivers lock-and-key chloride binding in triazolophanes

    K. P. McDonald, Y. Hua, S. Lee and A. H. Flood, Chem. Commun., 2012, 48, 5065
    DOI: 10.1039/C2CC17459F

Search articles by author

Spotlight

Advertisements